Cryolipolysis

Pmise CR-01

Name: Pmise CR-01
Brand: Pmise

Cryolipolysis fat freezing machine

CR-01 is a cryolipolysis platform built for one job: controlled cooling of localized subcutaneous fat. Love handles. Lower abdomen. Bra-line rolls. The pinchable pockets that survive a disciplined diet.

Core figures from our device manuals, so you can size this against whatever else is on your shortlist. Cooling setpoint runs 0 to 15 °C in 1 °C steps, with 14 °C the warmest step that still actively cools and 15 °C putting the system at ambient with cooling stood down. The timer covers 1-90 minutes in 1-minute increments. Vacuum intensity and infrared output each sit on a 0-8 scale. Vacuum frequency has four levels, where level I is a continuous hold and levels II-IV pulse up to roughly 0.7 Hz. Suction works between -0.02 and -0.09 MPa at up to 140 L/min. Maximum input draw is 1400 W, and the operator reads all of it off a 12.1-inch colour LCD.

Four applicators come in the box: two large at 165 x 81 mm, two small at 128 x 57 mm. Two run at once, so a flank pair gets treated symmetrically inside one appointment slot. Cooling is a combined water, air and semiconductor stack rather than a compressor alone, which is what keeps handle temperature steady through back-to-back sessions.

This unit anchors the fat-reduction half of our body contouring solutions. Browse the full equipment range if you're comparing platforms side by side.

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How it works

What the cold is actually doing

Adipocytes in the subcutaneous layer are more cold-sensitive than the skin, nerves and vessels sitting above them. Hold tissue in a narrow low-temperature window long enough and the lipids inside those cells crystallize, which sets off gradual cell death while the overlying dermis comes through intact. Manstein, Laubach and Anderson's group at the Wellman Center published the selective cryolysis work behind this in Lasers in Surgery and Medicine in 2008. The FDA's own overview of non-invasive body contouring describes the same sequence: pinchable fat drawn into an applicator, cooled, then cleared by the body over roughly two to three months.

Results are slow by design, then. Photograph your baselines properly, or you'll spend the follow-up consultation arguing about whether anything happened.

What each parameter on the panel controls

Set temperature (0 to 15 °C). The one that decides whether you're treating at all. Our archived protocol sheet puts a routine abdominal cycle at 1-4 °C. Park it at 15 °C between clients and the cooling stage stands down.
Suction power (0-8). Governs how much tissue gets drawn into the window and how firmly it holds against the cooling plates. Contact quality is everything here. A slack fold cools unevenly, and uneven cooling is what produces the ridge lines clients complain about.
Infrared output (0-8 in 1 W steps, 5-10 W at the handpiece). Local warmth for circulation and comfort during the cycle.
Suction frequency (I-IV). Level I holds steady vacuum, and that's what our manuals specify during cryo work. The pulsed levels exist for other handpiece uses.
Work time (1-90 min). Archived protocol default is 30 minutes per cycle.

Once the applicator is seated, none of this depends on hand technique. That changes your staffing maths: an operator sets parameters, verifies the seal, and the machine runs the cycle out on its own.

Applications

Localized subcutaneous fat on abdomen, flanks, back, outer thighs and upper arms
Reshaping after weight change or pregnancy
Contour refinement following liposuction, at practitioner discretion
Mild firming and texture improvement inside the treated zone

Where the indication stops

Cryolipolysis is not a weight-loss method and it is not a treatment for obesity. Cleared indications in the US are written around candidates at a BMI of 30 or below, which makes a sensible screening anchor even in markets that don't require that clearance. Cold-related conditions rule a client out entirely: cryoglobulinemia, cold urticaria, paroxysmal cold hemoglobinuria. So does a hernia at the treatment site.

Paradoxical adipose hyperplasia deserves a mention, because buyers rarely hear it from a vendor. The treated area firms and enlarges instead of shrinking. Large multicenter series report it as rare, though recent systematic review work in the aesthetic surgery literature argues it's underrecognized and underreported. Brief your clients on it, log your cycles, and refer anything that grows rather than shrinks.

Where CR-01 sits against our other body devices

Cryolipolysis and ultrasonic cavitation solve overlapping problems by different routes. CR-01 removes cells from a discrete, graspable bulge over a span of weeks. The SM-01 cavitation slimming system covers broader areas in shorter, more frequent visits and is far easier to package as a course. Skin laxity is a third question again, and the answer there is RF-01 radiofrequency tightening. Rooms running all three close more consultations, because the honest reply to "will this fix my stomach" is usually not one machine.

This page is technical documentation for trained operators, not medical advice. Candidate selection stays with a qualified practitioner.

Key advantages

Acceptance checks before you sign off

Ask for the compliance file, not a certificate screenshot. Medical electrical equipment in this class is designed against IEC 60601-1 for basic safety and essential performance, with the 60601-1-2 collateral covering electromagnetic disturbance. CE marking for the EU and your own national device registration are separate questions from both. Confirm which your importer actually needs before the crate ships, not after it clears customs.

Then check the boring things on arrival. Key switch, emergency stop, creepage protector, foot pedal interlock, and whether all four handle sockets report their cooling temperature independently on screen.

Install and running-cost reality

Power. Built for 220 V or 110 V at 50/60 Hz, plus or minus 10%. Outside that band you need a regulator rated above 3 kVA.
Room. 10-30 °C, 20-80% humidity, ventilated, out of direct sunlight.
Water. Roughly 1.8 L of pure or distilled water, filled with the machine switched off. Fill again after the first five minutes of running, because the handpieces and radiator hold a share of it. Change it monthly under heavy use. Never run the unit dry; the semiconductor stage won't forgive that.
Consumables. An antifreeze membrane plus a petrolatum layer, every session, no exceptions. Skipping the membrane is the most common operator error reported to us, and it's the one that causes real injury.
Filters. None. No lamp or filter replacement cycle to budget for, which is a genuine cost gap against light-based platforms.

Firmware updates go over USB. The interface switches between English and Chinese, useful if you're staffing a mixed team.

Specification

LP-LI Handpieces Parameters
Negative Pressure Intensity	-0.02MPa - -0.09MPa
Working Time	1-90mins (Step 1min)
IR Power	5W-10W
Temperature	0℃-15℃ (max cooling 14℃; 15℃ = ambient)
Suction Frequency	I-IV (Step I)
Window Size	165x81mm²
LP-SI Handpieces Parameters
Working Time	1-90mins (Step 1min)
Temperature	0℃-15℃ (max cooling 14℃; 15℃ = ambient)
Window Size	128x57mm²
Power	Max 1400W
Power Supply	220V 50Hz;110V 60Hz
Screen	12.1'' TFT touch screen
Net Weight	55kg
Gross Weight	70kg
Dimensions	82x54x244cm3

Frequently asked questions

How should we set parameters for a first abdominal session?

Our archived protocol sheet gives a starting point of 1-4 °C set temperature, suction power at level III-IV, infrared at IV-V, suction frequency at I, and 30 minutes on the timer. Treat that as a baseline, not a rule. Thinner clients and smaller tissue folds want a shorter cycle and gentler vacuum. Watch the per-handle temperature readouts through the first ten minutes, since that's when a poor seal announces itself.

How many sessions should a clinic quote?

Change emerges gradually over weeks as the body clears the affected cells, and repeat treatment on the same site is generally spaced around two months apart. Quote a course, review with photographs, and resist promising a fixed percentage of reduction. Any vendor handing you a precise number per cycle is quoting someone else's clinical trial run on someone else's applicator geometry.

Can two applicators run at the same time?

Yes, two handles can be selected and run together, which is how you keep bilateral zones symmetric within one appointment. The panel displays a separate cooling temperature for each active handle. One handle always stays selected, so the system won't let you deselect both.

What support ships with the machine?

An English manual covering installation, water filling, parameter guidance and routine maintenance, plus remote technical support and a walkthrough for your staff at first setup. Warranty terms and spare parts sit on our service page . Send your local voltage and intended treatment areas via contact and we'll spec the configuration.